Age |
|
100% - ↑ |
|
-
Guan et al.18 (1099)
-
Yang et al.19 (52)
-
Young et al.20 (18)
-
Ji et al.21 (NA)
-
Zhonghua22 (44672)
|
10 |
-
Liu et al.10 ≥ 60: OR 8.5 95% CI 1.6 - 44.8
-
Caramelo et al.12 50-59: OR 6.7 95% CI 2.9 - 15.2
-
≥ 80: OR 86.6 95% CI 32.6 - 202.4
-
Zhou et al.15 NA: OR 1.1 95% CI 1.0 - 1.2
|
●●● |
-
12 (5/17) = 29%
-
Median (IQR) Age, years
|
C- reactive protein |
-
Zhang et al.6 (19)
-
Li et al.11 (84)
-
Liu et al.10 (78)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
-
Wu et al.16 (201)
|
100% - ↑ |
|
-
Young et al.20 (18)
-
Guan et al.18 (1099)
|
6 |
|
●●● |
|
D- Dimer |
-
Tang et al.13 (183)
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Wang et al.7 (138)
-
Liu et al.9 (109)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
6 |
|
●●● |
|
Albumin |
-
Liu et al.10 (78)
-
Huang et al.17 (41)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↓ |
|
|
5 |
|
●●● |
|
Body temperature |
-
Huang et al.17 (41)
-
Li et al.11 (84)
-
Liu et al.10 (78)
-
Wu et al.16 (201)
|
75% - ↑ |
|
-
Guan et al.18 (1099)
-
Young et al.20 (18)
|
3 |
|
●●● |
|
SOFA score |
-
Liu et al.9 (109)
-
Zhou et al.15 (191)
|
100% - ↑ |
|
|
2 |
|
●●● |
|
Diabetes |
|
100% - Presence |
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Liu et al.10 (78)
-
Ruan et al.14 (150)
|
-
Guan et al.18 (1099)
-
Zhonghua22 (44672)
-
Yang et al.19 (52)
|
2 |
|
●●● |
-
13 (0/13) = 0%
-
Percentages Diabetes, NA
|
Lymphocyte count |
-
Zhang et al.6 (19)
-
Li et al.11 (84)
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
-
Wu et al.16 (201)
-
Zhou et al.15 (191)
|
100% - ↓ |
-
Yang et al.19 (52)
-
Liu et al.10 (78)
|
-
Young et al.20 (18)
-
Guan et al.18 (1099)
|
6 |
|
●●○ |
|
Dyspnea |
-
Li et al.11 (84)
-
Huang et al.17 (41)
-
Tian et al.8 (262)
-
Wang et al.7 (138)
-
Ruan et al.14 (150)
-
Wu et al.16 (201)
|
100% - Presence |
|
-
Yang et al.19 (52)
-
Guan et al.18 (1099)
-
Young et al.20 (18)
|
5 |
|
●●○ |
-
10 (0/10) = 0%
-
Percentages Dyspnea, NA
|
White blood Cell count |
-
Huang et al.17 (41)
-
Wang et al.7 (138)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
-
Zhang et al.6 (19)
|
100% - ↑ |
-
Li et al.11 (84)
-
Liu et al.10 (78)
|
-
Guan et al.18 (1099)
-
Young et al.20 (18)
|
5 |
|
●●○ |
|
Procalcitonin |
-
Li et al.11 (84)
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Liu et al.9 (109)
-
Zhou et al.15 (191)
|
100% - ↑ |
|
|
4 |
|
●●○ |
|
Lactate dehydrogenase |
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Liu et al.9 (109)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
-
Young et al.20 (18)
-
Guan et al.18 (1099)
|
4 |
|
●●○ |
-
7 (1/8) = 13%
-
Median (IQR) LDH, U/L
|
Cardiac troponins |
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
|
100% - ↑ |
|
|
4 |
|
●●○ |
|
Prothrombin time |
-
Huang et al.17 (41)
-
Tang et al.13 (183)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
3 |
|
●●○ |
|
Blood urea nitrogen |
-
Ruan et al.14 (150)
-
Liu et al.9 (109)
-
Wang et al.7 (138)
|
100% - ↑ |
|
|
3 |
|
●●○ |
|
Total bilirubin |
-
Ruan et al.14 (150)
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Wu et al.16 (201)
|
100% - ↑ |
|
-
Yang et al.19 (52)
-
Guan et al.18 (1099)
|
3 |
|
●●○ |
-
4 (3/7) = 43%
-
Total bilirubin, μmol/L
|
Interleukin-6 |
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
3 |
|
●●○ |
-
3 (0/3) = 0%
-
Median (IQR) IL-6, pg/mL
|
Serum ferritin |
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
3 |
|
●●○ |
|
Comorbidity |
-
Li et al.11 (84)
-
Wang et al.7 (138)
-
Zhang et al.6 (19)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
|
100% - Presence |
-
Huang et al.17 (41)
-
Tang et al.13 (183)
|
-
Guan et al.18 (1099)
-
Yang et al.19 (52)
|
3 |
|
●●○ |
|
Neutrophil count |
-
Huang et al.17 (41)
-
Wang et al.7 (138)
-
Liu et al.9 (109)
-
Wu et al.16 (201)
|
75% - ↑ |
-
Liu et al.10 (78)
-
Li et al.11 (84)
|
|
2 |
|
●●○ |
|
Creatine kinase MB |
-
Wang et al.7 (138)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
2 |
|
●●○ |
-
4 (0/4) = 0%
-
Median (IQR) CK-MB, U/L
|
CURB-65 |
|
100% - ↑ |
|
|
2 |
|
●●○ |
|
Respiratory rate |
-
Huang et al.17 (41)
-
Liu et al.10 (78)
-
Tian et al.8 (262)
-
Zhou et al.15 (191)
|
100% - ↑ |
-
Li et al.11 (84)
-
Wang et al.7 (138)
|
|
2 |
|
●●○ |
|
Lymphocyte ratio |
|
100% - ↓ |
|
|
1 |
|
●●○ |
|
Chronic kidney disease |
-
Liu et al.9 (109)
-
Zhou et al.15 (191)
|
100% - Presence |
|
|
1 |
|
●●○ |
|
Chest pain |
|
100% - Presence |
|
|
1 |
|
●●○ |
|
Neutrophil ratio |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
Fibrinogen degradation product |
|
100% - ↑ |
|
|
1 |
|
●●○ |
-
1 (0/1) = 0%
-
Median (IQR) FDP, ug/mL
|
Myoglobin |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
APACHE II |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
PaO2:FiO2 |
|
100% - ↓ |
|
|
1 |
|
●●○ |
|
Globulin |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
Prealbumin |
|
100% - ↓ |
|
|
1 |
|
●●○ |
|
Urea |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
Glucose |
|
100% - ↑ |
|
|
1 |
|
●●○ |
-
1 (0/1) = 0%
-
Median (IQR) Glucose, mM
|
Cholinesterase |
|
100% - ↓ |
|
|
1 |
|
●●○ |
|
Cystatin C |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
α-HBDH |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
LDL |
|
100% - ↓ |
|
|
1 |
|
●●○ |
-
1 (0/1) = 0%
-
Median (IQR) LDL, mM
|
Heart Rate |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
Health system burden in Hubei |
|
100% - ↑ |
|
|
1 |
|
●●○ |
|
Days from onset of symptoms to hospital |
-
Li et al.11 (84)
-
Wang et al.7 (138)
-
Tian et al.8 (262)*
|
100% - ↑ |
-
Zhang et al.6 (19)
-
Zhou et al.15 (191)
|
|
1 |
|
●●○ |
|
O2 saturation |
|
100% - ↓ |
|
|
0 |
|
●●○ |
|
Fibrinogen |
|
100% - ↑ |
|
|
0 |
|
●●○ |
|
Smoking |
|
100% - Presence |
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Zhou et al.15 (191)
|
-
Guan et al.18 (1099)
-
Yang et al.19 (52)
|
-2 |
|
●●○ |
|
Chronic respiratory disease |
|
100% - Presence |
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Wang et al.7 (138)
-
Liu et al.10 (78)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
|
-
Yang et al.19 (52)
-
Zhonghua22 (44672)
-
Guan et al.18 (1099)
|
-3 |
|
●●○ |
-
10 (2/12 = 17%)
-
Percentages COPD, NA
|
Cancer |
|
100% - Presence |
-
Huang et al.17 (41)
-
Liu et al.10 (78)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
|
-
Zhonghua22 (44672)
-
Guan et al.18 (1099)
|
-3 |
|
●●○ |
|
Cardiovascular disease |
|
100% - Presence |
-
Huang et al.17 (41)
-
Wang et al.7 (138)
-
Liu et al.9 (109)
-
Zhang et al.6 (19)
-
Liu et al.10 (78)
-
Li et al.11 (84)
-
Wu et al.16 (201)
|
-
Guan et al.18 (1099)
-
Yang et al.19 (52)
-
Zhonghua22 (44672)
|
-4 |
|
●●○ |
|
Lactate |
|
100% - ↑ |
|
-
Yang et al.19 (52)
-
Wang et al.7 (138)
|
-1 |
|
●○○ |
|
Monocyte count |
|
100% - ↓ |
-
Wang et al.7 (138)
-
Wu et al.16 (201)
|
|
-1 |
|
●○○ |
|
Creatinine |
-
Ruan et al.14 (150)
-
Wang et al.7 (138)
-
Zhou et al.15 (191)
|
100% - ↑ |
-
Liu et al.10 (78)
-
Huang et al.17 (41)
-
Liu et al.9 (109)
-
Wu et al.16 (201)
|
-
Yang et al.19 (52)
-
Guan et al.18 (1099)
|
-1 |
|
●○○ |
|
Composite abnormal radiological findings (CT-RX) |
-
Li et al.11 (84)
-
Zhou et al.15 (191)
|
100% - ↑ |
-
Wang et al.7 (138)
-
Zhang et al.6 (19)
-
Huang et al.17 (41)
|
-
Young et al.20 (18)
-
Guan et al.18 (1099)
|
-1 |
|
●○○ |
|
Systolic blood pressure |
|
100% - ↑ |
-
Tian et al.8 (262)*
-
Zhou et al.15 (191)
|
-
Yang et al.19 (52)
-
Young et al.20 (18)
|
-1 |
|
●○○ |
|
Platelet count |
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
|
100% - ↓ |
-
Wang et al.7 (138)
-
Liu et al.10 (78)
-
Wu et al.16 (201)
|
-
Yang et al.19 (52)
-
Tang et al.13 (183)
-
Young et al.20 (18)
-
Guan et al.18 (1099)
-
Huang et al.17 (41)
|
-1 |
|
●○○ |
|
AST |
-
Wang et al.7 (138)
-
Wu et al.16 (201)
|
100% - ↑ |
|
|
-1 |
|
●○○ |
|
ALT |
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Zhou et al.15 (191)
|
100% - ↑ |
-
Liu et al.10 (78)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
-
Wu et al.16 (201)
|
|
-1 |
|
●○○ |
|
Expectoration |
|
100% - Presence |
-
Wang et al.7 (138)
-
Huang et al.17 (41)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
|
|
-3 |
|
●○○ |
-
6 (0/6) = 0%
-
Percentages Sputum, NA
|
Cough |
-
Li et al.11 (84)
-
Zhang et al.6 (19)
|
100% - Presence |
-
Huang et al.17 (41)
-
Tian et al.8 (262)
-
Wang et al.7 (138)
-
Liu et al.10 (78)
-
Liu et al.9 (109)
-
Ruan et al.14 (150)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
-
Yang et al.19 (52)
-
Guan et al.18 (1099)
-
Young et al.20 (18)
|
-6 |
|
●○○ |
-
11 (2/13) = 15%
-
Percentages Cough, NA
|
Fatigue |
|
100% - Presence |
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Tian et al.8 (262)
-
Wang et al.7 (138)
-
Ruan et al.14 (150)
-
Wu et al.16 (201)
-
Zhou et al.15 (191)
|
|
-6 |
|
●○○ |
-
5 (2/7) = 29%
-
Percentages Fatigue, NA
|
Male gender |
|
100% - Presence |
-
Huang et al.17 (41)
-
Zhang et al.6 (19)
-
Wang et al.7 (138)
-
Tian et al.8 (262)
-
Liu et al.9 (109)
-
Li et al.11 (84)
-
Ruan et al.14 (150)
-
Liu et al.10 (78)
-
Zhou et al.15 (191)
-
Wu et al.16 (201)
|
-
Guan et al.18 (1099)
-
Yang et al.19 (52)
-
Zhonghua22 (44672)
-
Young et al.20 (18)
|
-8 |
|
●○○ |
-
15 (1/16) = 6%
-
Percentages Male, NA
|